
The main villain is Dylan Blake, still somehow one of the most chaotic and chilling antagonists with his constant tendency to put a gun to his head with one bullet in the chamber and play solo Russian Roulette. There are also some callbacks to Resident Evil 2 and 4 like Leon clearing the Lickers in the sewers by shooting a gasoline canister to blow them up, Leon's knife fight with Jill, and the team slowly turning from the new virus form. Taylor invoking the Harvardville Airport incident from Degeneration.

You have some references here and there to previous installments like Jill Valentine still reflecting on being turned against Chris by Wesker in Resident Evil 5 and Dr. Resident Evil: Death Island takes place one year after the events of Vendetta and still doesn't fill in the blanks to the seventh game – Biohazard.
